In midweek, Manchester United defeated Brentford 3-1 to end their two-game winless streak in the top flight.
Rangnick’s side lie seventh in the Premier League table. United have lost just once in the league under his leadership, but there are still some concerns about the side’s shaky defense, which could be exposed by West Ham on Saturday.
In the last 15 Premier League home games, Manchester United have kept just one clean sheet.
Cristiano Ronaldo has been suffering from a neck injury.
At the weekend, David Moyes’s Hammers were beaten 3-2 by Leeds United on their own turf, ending their four-game winning streak in all competitions.
As a reminder, West Ham currently sit just 2 points above Man United, having played one game more, and Moyes’s side beat United at Old Trafford in the EFL Cup earlier this season.
Moyes has never won a Premier League away match at Old Trafford in 14 attempts (D4 L10).
David Moyes’s side have won their last two away games at Watford and Crystal Palace, scoring seven goals, but it is notable that the Eagles are the highest-ranked team among the six David Moyes’s side have beaten away from home.
Manchester United vs West Ham betting tip: Double Chance West Ham/Draw @ 2.00